I'm also experiencing inactive neighbor problems. The biggest issue for me is lack of trading. The neighborly help is a plus in the game, but can be overlooked, imo. I seem to have only 1 neighbor(discovered) who posts trades and he/she is much more advanced than me. So the trades are far to large in quantity for me to accommodate. I have messaged this player requesting smaller amounts, but to no avail. I have had a few random trades taken from time to time, but not nearly what I need. I am resigned to producing unboosted goods and waiting a long time to accomplish my goals. I am currently holding 10 knowledge points and have no way to spend them until I get enough goods to unlock the next tech. Meanwhile, any advancement on my world map is rather in vein as I don't get the new knowledge points I deserve.
I'm not sure what can be done about this as I don't think neighborhood shuffling is in the plans. At least I don't see how this would be accomplished...you would lose the present advancement on solved provinces, wouldn't you?