@reinhardz And now imagine, when i was begining, my first big event after i started playing (at that time it was 4 big events / year), there were quests of paying thousands of T1,T2 & T3 goods (T3 are unlocked in ch3), so unfinishable without help in the first half of ch3 or ch2/1.
My advice: Just pick up some nice pure culture building and don't worry about not finishing the quest line and concentrate on advancing your city.
There will be plenty of time to finish later events, there's nothing you can't miss yet (evos/sets).